Objective:

To report a case of hair repigmentation and regrowth during baricitinib treatment in a patient with canities subita and concurrent alopecia areata.

Approach:

Key Findings:

• Complete hair repopulation occurred along with resolution of the alopecic patch.
• Hair regrowth was denser and grayer rather than returning to baseline pigmentation.
• No adverse events were reported, and rheumatoid arthritis remained in remission.

Interpretation:

The case supports a potential link between canities subita and alopecia areata, but does not establish baricitinib as an effective treatment for canities subita.

Limitations:

• Single-patient case report design without a comparator group.
• Lack of standardized alopecia severity or pigmentation outcomes.
• Clinical diagnosis made without histopathologic confirmation.
• Concurrent withdrawal of etanercept may have confounded results.

Conclusion:

The report should not be interpreted as establishing baricitinib as an effective treatment for canities subita, and its use would be off-label.

Sources:

• International Journal of Trichology
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