A prospective cohort study of 344 patients undergoing elective colorectal surgery found that 51% managed postdischarge pain without any opioids over 30 days, with similar opioid-free rates across open (47%), laparoscopic (51%), and stoma procedures (52%). Conducted at two Canadian academic hospitals, the study identified older age, fewer opioid pills prescribed at discharge, absence of postdischarge cannabis use, and higher patient activation as predictors of opioid-free recovery. With 92% of patients receiving discharge opioid prescriptions (median 13 pills), the authors suggest that prescriber stewardship targeting prescription size and patient education may help reduce unnecessary opioid consumption following colorectal procedures.
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