1. Human fibrinogen concentrate (FC) reduces surgical blood loss.
2. Randomized trial involved 222 patients in Europe.
3. Mean blood loss: FC 1381 mL vs FFP/Cryo 1660 mL.
4. FC achieved fibrinogen target levels faster.
5. Lower rebleeding and thromboembolic events noted in FC group.
6. FC administration was quicker than FFP/Cryo.
7. No treatment-related deaths in the study.

Source: eClinicalMedicine