"These data highlight the role of subjective patient-related parameters in the response to cytokine inhibition and suggest that a high-volume representation of the disease in the CNS—involving more frontal-associative brain circuits—increases the likelihood to respond to TNF inhibitor.
Rituximab-treated patients with rheumatic disease had diminished antibody levels and impaired CD8+ T-cell responses after SARS-CoV-2 infection and vaccination, though CD4+ responses remained intact.
Clinics and health plans are expanding telehealth services as increased immigration enforcement has coincided with some patients, including immigrant families, delaying or avoiding in-person medical visits.
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Large-scale genetic analyses identify multiple susceptibility loci for Takayasu arteritis, confirming HLA-B*52 as the strongest association and revealing immune pathways that vary by ancestry.
Nearly 1 in 10 individuals with myalgic encephalomyelitis/chronic fatigue syndrome reported voice or speech changes in a recent survey, despite not being directly asked about these symptoms.
Patients with psoriatic arthritis consistently identify nonjoint symptoms such as dactylitis, psoriasis, and uveitis, demonstrating the clinical utility of patient-reported outcome measures.
Researchers studying nearly 29,000 middle-aged adults in Sweden found that individuals with asthma had significantly higher rates of hypertension, diabetes, and other conditions, along with elevated levels of systemic inflammation and blood sugar markers.