July 15, 2025

Genetic Markers Don’t Guide RA Drug Choice

A large UK study found no significant difference in treatment effectiveness between abatacept and adalimumab for rheumatoid arthritis, regardless of patients’ HLA-DRB1 genetic profiles.

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July 15, 2025

Methotrexate Shows No Knee OA Symptom Benefit, Study Finds

A 52-week randomized clinical trial found no significant difference between methotrexate and placebo in reducing pain or effusion-synovitis in patients with inflammatory knee osteoarthritis.

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July 14, 2025

Skin Autoimmune Disorders Tied to Longer Cancer Survival

A large nationwide study in Taiwan found that patients with autoimmune skin diseases had lower all-cause and cancer-specific mortality following cancer treatment compared with those without these conditions.

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June 30, 2025

Can Typos Change a Diagnosis?

Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.

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June 26, 2025

MRI Finds Hidden Arthritis After Cancer Therapy

A new imaging study found that patients who develop joint pain after cancer immunotherapy often show significant inflammation and joint damage on MRI—even when physical signs of arthritis are absent.

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June 23, 2025

Central Body Fat Tied to Psoriasis Risk: Study

A large UK study of more than 336,000 adults found that central body fat, especially around the abdomen, was strongly linked to a higher risk of psoriasis, with the association more pronounced in women and independent of genetic risk.

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June 23, 2025

Methotrexate Adds No Psoriasis Benefit to Adalimumab

The addition of methotrexate to adalimumab for the treatment of plaque psoriasis may not improve drug survival, efficacy, or safety compared with adalimumab alone, according to a large real-world cohort study.

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June 18, 2025

Does Depression Predict Pain Later?

A long-term study of older adults found that symptoms of depression and loneliness began increasing years before the onset of pain and remained elevated afterward, especially in people with lower income or education levels.

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June 17, 2025

Aconitine Tames Joints, Protects Bone

At EULAR 2025, researchers presented data showing aconitine reduced bone erosion and increased regulatory T cells in a rheumatoid arthritis mouse model.

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