Large-scale genetic analyses identify multiple susceptibility loci for Takayasu arteritis, confirming HLA-B*52 as the strongest association and revealing immune pathways that vary by ancestry.
Nearly 1 in 10 individuals with myalgic encephalomyelitis/chronic fatigue syndrome reported voice or speech changes in a recent survey, despite not being directly asked about these symptoms.
Patients with psoriatic arthritis consistently identify nonjoint symptoms such as dactylitis, psoriasis, and uveitis, demonstrating the clinical utility of patient-reported outcome measures.
Researchers studying nearly 29,000 middle-aged adults in Sweden found that individuals with asthma had significantly higher rates of hypertension, diabetes, and other conditions, along with elevated levels of systemic inflammation and blood sugar markers.
JAK inhibitor therapy targets inflammation and correlates with improvements in carotid artery measurements, while baseline vascular markers continue to predict cardiovascular risk.
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Patients undergoing shoulder arthroplasty for rheumatoid arthritis show significant pain and function improvement, and data suggest emotional status may influence recovery dynamics over time.
“The approval of the SetPoint System, the first-in-class neuroimmune modulation platform, represents a transformative milestone in the management of autoimmune diseases."
A 52-week randomized clinical trial found no significant difference between methotrexate and placebo in reducing pain or effusion-synovitis in patients with inflammatory knee osteoarthritis.