"Burosumab treatment normalized ALP serum levels in about 80% of both pediatric and adolescent cohorts, suggesting a substantial improvement of rickets in these patients," report authors of comprehensive new evidence-based recommendations for X-linked hypophosphatemia management.
NIH director, Dr. Monica M. Bertagnolli, is stepping down after launching major initiatives in women's health and long COVID research, indicating optimism for their continuation under new leadership.
"Screening in higher-risk women 65 years or older was associated with a small absolute risk reduction in hip and major fractures compared with usual care."
Researchers examined associations between body composition factors, such as fat and muscle mass, and health-related quality of life outcomes in patients with knee and hip osteoarthritis.
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A study reveals that while Notch signaling drives early RA pathology through neovascularization, anti-TNF therapy specifically reduced JAG1/2 and DLL1/4 transcription in synovial tissue myeloid cells, but only in good responders (ΔDAS28 >1.2 with DAS28 ≤3.2 at 12 weeks).
Researchers present new insights into Relative Energy Deficiency in Sport, emphasizing its impact on athletes and military personnel, and discussing potential prevention and treatment strategies.
New research reveals that men's HDL cholesterol follows an inverted U-shaped relationship with vitamin D levels, while women maintain a consistently positive correlation.