5 Key Takeaways

• 1

  An international team has developed the first classification criteria for pediatric chronic nonbacterial osteomyelitis (CNO).

• 2

  The criteria were created through a four-phase process involving expert consensus and patient perspectives across 31 centers globally.

• 3

  To classify as having CNO, a child must be under 18, experience bone pain for at least six weeks, and show abnormal imaging findings.

• 4

  A minimum score of 55 points based on nine features is required for classification, without the need for a bone biopsy.

• 5

  The criteria demonstrated 82% sensitivity and 98% specificity, providing a standardized tool for research and clinical trials.