- High-risk RA patients have a 20% ILD development rate in 15 years.
- Study involved 2,507 patients from the VA RA registry.
- Composite biomarker score was created from 8 proteins.
- ILD prediction improved with added clinical factors.
- Matrix metalloproteinase-7's role was significant.
- Generalizability of findings is uncertain due to the sample population.
- Blood biomarkers may enable early monitoring and intervention.
Source: Arthritis and Rheumatology