- Aconitine, a compound in Aconiti Lateralis Radix Praeparata, shows potential in rheumatoid arthritis.
- The study evaluated aconitine’s effects on arthritis severity, synovial inflammation, and bone erosion.
- Aconitine led to a significant reduction in bone erosion but showed a nonsignificant trend in arthritis severity.
- Flow cytometry analyses revealed an increase in regulatory T cells' proportion in the spleen and joint-draining lymph nodes due to aconitine.
- The study was conducted by investigators from Peking University People’s Hospital and Dongfang Hospital Beijing University of Chinese Medicine.
Source: EULAR 2025, Abstract ABS0005: "Aconitine: A Potential Treatment for Rheumatoid Arthritis"
