A cohort study analyzed the incidence and stability of remission in 692 young individuals at clinical high risk for psychosis, revealing that remission rates vary significantly depending on the criteria used. The research showed a 7% remission rate at 2 months based on symptoms alone, while 4% met the more stringent symptoms-and-function criteria. Participants who had multiple prior remissions were more likely to remain in stable remission, highlighting the dynamic nature of clinical high-risk status. The study suggests a need for ongoing assessments and cautions in interpreting medication effects.

Source: JAMA Network Open