- Meta-analysis of 49 trials with 39,336 patients analyzed BSH discontinuation strategies.
- Pharmacist-led education resulted in 491 more discontinuations per 1,000 patients.
- Patient education led to 144 additional discontinuations.
- Moderate-certainty evidence showed little effect on mental health.
- Tapering also supported discontinuation but with uncertain impact on quality of life.
- CBT showed uncertain effects on insomnia and sleep efficiency.
- Multicomponent strategies may be more effective.
Source: thebmj
