- A clinical trial compared oral and injectable naltrexone in hospitalized patients with alcohol use disorder.
- Both forms demonstrated similar reductions in heavy drinking with no statistically significant difference in outcomes.
- Injectable naltrexone showed higher medication adherence but had substantially higher costs.
- Phosphatidylethanol levels indicated recent heavy alcohol use in 75.9% of tested participants.
- Treatment choice for alcohol use disorder may be guided by patient preference, cost, and likelihood of adherence.
Source: JAMA Internal Medicine