- Higher citrus consumption associated with 22% lower risk of incident depression.
- 15 gut microbial species linked to citrus intake, with potential impact on depression.
- F. prausnitzii enriched among those with higher citrus intake inversely associated with depression.
- Citrus-specific effect observed, not significant for total fruit or vegetable intake.
- Naringenin and formononetin linked to lower depression risk; study observational, cannot establish causality; limited generalizability due to the study population.
Source: Microbiome