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Conexiant chevron_right Psychiatry chevron_right Antidepressants May Benefit IBD Through Shared Mechanisms
From the Journals

Antidepressants May Benefit IBD Through Shared Mechanisms

Researchers examine how inflammatory bowel disease and depression share biological mechanisms and how treating one may improve outcomes in the other.

Conexiant
Full Article Summary Notecard
  1. Some IBD patients may benefit from antidepressant treatment.
  2. Biologics like ustekinumab can cause depression in patients without prior conditions.
  3. 20.1% of U.S. IBD patients experience depressive disorders.
  4. Crohn's disease shows a stronger association with psychiatric comorbidities than ulcerative colitis.
  5. Shared susceptibility loci across IBD and depression include NOD2 and IL23R. 

Source: Journal of Clinical Medicine

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