Fetal hematopoietic stem cells in Down syndrome are 'primed' for differentiation, as revealed by single-cell multi-omics of over 1.1 million cells, potentially explaining early hematological abnormalities.
In a phase 3 trial, 67% of children treated with omalizumab tolerated 600 mg of peanut protein, a dramatic increase over just 7% with placebo, highlighting omalizumab’s potential in managing pediatric food allergies.
New research compares human milk antibody levels against infectious pathogens across different income countries, revealing important insights for infant health.
Two phase III clinical trials reveal promising results of once-daily roflumilast cream, 0.15%, in improving symptoms of atopic dermatitis within 4 weeks.
New analysis reveals U.S. nonprofit hospitals received $37.4 billion in tax benefits in 2021, with more than half attributed to state and local taxes. The benefits varied significantly by state and were concentrated among a small number of hospitals.
From overflowing cribs to empty pediatric wings, new data reveals a 133.3% difference in children's hospital bed occupancy rates between the most and least crowded states.
Beyond salary and work-life balance, physicians seeking new roles should evaluate potential employers' governance, reward systems, and culture, according to a viewpoint published in JAMA Internal Medicine.