1. HPV vaccination reduced infections by up to 98%.
2. Unvaccinated patients showed herd protection with declines up to 76%.
3. Vaccine coverage increased from 0% in 2006 to 82% in 2023.
4. More than half had a prior STI, and most reported multiple partners.
5. Study limits included single region, fewer unvaccinated patients, and assay changes.
6.  “Herd protection was observed in unvaccinated patients despite high-risk sexual behaviors,” said Morgan DeSieghardt, PhD, Cincinnati Children’s Hospital.
7. “There should be no complacency… scale up vaccination-related programming,” wrote Teresa A. Imburgia, MD, and Rachel A. Katzenellenbogen, MD, University of Washington and Seattle Children’s.

Source: JAMA Pediatrics and Editorial