- COVID-19 vaccination during pregnancy modeled to prevent thousands of hospitalizations in US infants and mothers.
- Universal maternal vaccination projected to avert ~2,500 infant and ~450 maternal hospitalizations.
- At 50% coverage: ~1,250 infant and ~228 maternal hospitalizations prevented.
- Infants <6 months face risks similar to adults aged 65–74, despite being ineligible for vaccination.
- Model used COVID-NET data; assumed vaccine effectiveness of 35% for infants and 33% for mothers.
- Study limitations: reliance on recent incidence, observational effectiveness estimates, and low maternal vaccine uptake.
Source: JAMA Pediatrics