A woman with a decades-long history of intensely pruritic, nonblistering papules on her extremities was diagnosed with dystrophic epidermolysis bullosa pruriginosa, confirmed by COL7A1 gene sequencing, after a comprehensive clinicopathologic evaluation.
A 6-protein blood-based model predicted kidney function decline in patients with ADPKD more accurately than clinical or imaging-based models, and offers a new pathway for outcome prediction.
A new study identified human pegivirus in the brains and blood of patients with Parkinson’s disease, revealing virus-linked immune and gene expression changes that varied by genetic background.
Chemotherapy, while targeting cancer cells, also leaves a lasting mark on normal blood cells by introducing DNA mutations that can persist for decades.
Scientists engineered E. coli to perform a synthetic chemical reaction that enables the conversion of plastic waste into the common drug paracetamol using a non-toxic, phosphate-driven process inside living cells.
A new study found that genetic differences in the AMY1 gene, which affects salivary amylase production, along with dietary starch, influence the types and diversity of bacteria that form in oral biofilms—key players in dental caries and gum disease.