July 23, 2025

6 Blood Proteins Predict Kidney Function Decline

A 6-protein blood-based model predicted kidney function decline in patients with ADPKD more accurately than clinical or imaging-based models, and offers a new pathway for outcome prediction.

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July 21, 2025

Melanoma Risk Differs by Mole Count and Genetic Profile

A large study found distinct genetic and phenotypic risk patterns for nevus-associated and de novo invasive melanomas.

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July 15, 2025

Genetic Markers Don’t Guide RA Drug Choice

A large UK study found no significant difference in treatment effectiveness between abatacept and adalimumab for rheumatoid arthritis, regardless of patients’ HLA-DRB1 genetic profiles.

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July 14, 2025

Pegivirus in Brain Linked to Parkinson’s Disease

A new study identified human pegivirus in the brains and blood of patients with Parkinson’s disease, revealing virus-linked immune and gene expression changes that varied by genetic background.

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July 09, 2025

Chemotherapy Leaves Long-Lasting DNA Scars in Blood

Chemotherapy, while targeting cancer cells, also leaves a lasting mark on normal blood cells by introducing DNA mutations that can persist for decades.

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July 07, 2025

Saliva Test May Signal Diabetes-Linked Metabolic Changes

Salivary enzyme levels tied to AMY1 gene copy number may help indicate type 2 diabetes or prediabetes status, new cross-sectional study suggests.

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July 07, 2025

Can Gene Therapy Restore Hearing?

A new gene therapy trial shows rapid, significant hearing improvement in children and adults with inherited deafness caused by OTOF mutations.

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July 07, 2025

Gene-Starch Interaction Alters Oral Bacteria Balance

A new study found that genetic differences in the AMY1 gene, which affects salivary amylase production, along with dietary starch, influence the types and diversity of bacteria that form in oral biofilms—key players in dental caries and gum disease.

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July 03, 2025

Is HPV-Driven SNSCC Its Own Disease?

Researchers identified key genetic differences between HPV-associated and HPV-independent sinonasal squamous cell carcinoma, revealing distinct mutations, survival risks, and potential treatment targets.

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