- Insomnia symptoms were linked to a higher risk of ischemic stroke but not to all stroke types combined
- Diagnosed insomnia showed stronger and broader associations, including increased risk of any stroke
- Results differed depending on analytic approach, with odds ratio–based analyses suggesting associations with overall stroke risk
- Mendelian randomization analyses did not show a clear association with overall stroke but suggested a small link with ischemic stroke
- Study limitations included heterogeneity in insomnia definitions, reliance on self-reported data, and lack of studies from low-income regions
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