Rural emergency rooms across the U.S. are increasingly staffed by physician assistants and nurse practitioners instead of physicians, raising debates over care quality, staffing shortages, and access to emergency services.
Researchers compare long-term outcomes of two biologics in managing Crohn’s disease of the pouch, focusing on clinical response, remission rates, and adverse event profiles in a real-world multicenter setting.
CDC workers describe stalled HIV prevention projects, morale collapse, and heightened safety fears after budget cuts, layoffs, and a deadly shooting at agency headquarters.
Large-scale genetic analyses identify multiple susceptibility loci for Takayasu arteritis, confirming HLA-B*52 as the strongest association and revealing immune pathways that vary by ancestry.
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Subgroup analyses demonstrated a greater reduction in neurologic events than psychiatric events, though the reduction in psychiatric events was not statistically significant.
A phase 3 randomized trial found that Moderna’s next-generation COVID-19 vaccine, mRNA-1283, was non-inferior to the earlier mRNA-1273 vaccine in preventing COVID-19 and produced stronger neutralizing antibody responses.