February 21, 2025

Environmental vs. Genetic Risk in Aging and Mortality

Researchers quantify the exposome's greater impact on aging and mortality risk compared with genetic predisposition, identifying 25 key environmental risk factors.

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February 21, 2025

FDA Approves First Cerebrotendinous Xanthomatosis Treatment

The FDA has approved Ctexli (chenodiol) as the first treatment for cerebrotendinous xanthomatosis, a rare lipid storage disorder.

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February 20, 2025

Hospital Occupancy to Reach 85% by 2035

The projection is driven by a decline in staffed beds and an aging population.

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February 20, 2025

Study Links Parental Drinking to Offspring Cancer Risk

New research in mice suggests that parental alcohol use before conception may predispose male offspring to increased liver cancer susceptibility through epigenetic changes in mitochondrial function. The study identifies mitochondrial dysfunction and inflammation as key mechanisms, with dual-parental exposure producing the most severe effects.

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February 19, 2025

GALAD Score Enhances HCC Surveillance Accuracy

GALAD score improves hepatocellular carcinoma detection within 12 months of diagnosis, outperforming AFP in sensitivity and specificity, study shows.

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February 18, 2025

FDA Qualifies Two-Level RDL for AUD Trials

The drug development tool offers an alternative, clinically meaningful endpoint in clinical trials that evaluate pharmacologic treatments for alcohol use disorder.

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February 17, 2025

Physician Turnover After Private Equity Exits

Researchers found physicians in private equity-exiting practices were less likely to stay and more likely to join larger groups within 2 years.

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February 17, 2025

Skin Metabolism and Exudation Limit Tattoo Ink Absorption, Study Finds

Researchers examined systemic absorption, metabolism, and excretion of tattoo ink tracers, providing evidence for a cutaneous first-pass effect and measuring systemic exposure levels.

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February 17, 2025

Broccoli Sprout Extract in Prediabetes: Microbiota and Glycemic Variability

Researchers examined the effects of broccoli sprout extract on fasting glucose in prediabetes and observed variability in glycemic response potentially linked to microbiota composition.

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