Fetal hematopoietic stem cells in Down syndrome are 'primed' for differentiation, as revealed by single-cell multi-omics of over 1.1 million cells, potentially explaining early hematological abnormalities.
Mailing educational brochures before appointments led to a 29.5% deprescribing rate, compared to 25.8% in controls, suggesting a simple intervention can significantly shift medication management.
A recent study found that topical vitamin D was associated with a reduction in proinflammatory cytokine levels and the severity of inflammatory acne lesions. Additional studies are needed to gain a clearer understanding of its mechanism of action.
New research reveals that men's HDL cholesterol follows an inverted U-shaped relationship with vitamin D levels, while women maintain a consistently positive correlation.
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Close to 75% of women with polycystic ovary syndrome were screened for diabetes, but only 19% were screened using the recommended oral glucose tolerance test.
A meta-analysis of 99 randomized controlled trials reveals vitamin D supplementation significantly improved cardiometabolic risk factors, with more pronounced benefits observed in non-Western populations, individuals with lower baseline 25[OH]D levels, and those with lower BMI.