- A 7-day antibiotic regimen was found to be noninferior to 14 days for Gram-negative bloodstream infections in hospitalized adults.
- A new analysis included 3,729 adult patients from 4 randomized clinical trials.
- 51.3% of participants were women; most infections were caused by Enterobacterales bacteria.
- ITT analysis showed 97.8% probability of noninferiority for 7-day regimen.
- Certainty of evidence rated high using GRADE criteria.
Source: JAMA Network Open