Gastroenterology
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Liver Disease

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October 02, 2025

A New Hub for Liver Research Tackles Its First Investigations

Mount Sinai's newly launched Institute for Liver Research has funded its first two pilot projects, chosen from among 11 applications submitted by basic, translational, or clinical research teams, and awarded one-year grants of $30,000 each in hopes of generating preliminary data sufficient to stimulate broader funding and research collaborations. One project focuses on genomics and genetic sequencing of patients to determine how many and which abnormalities are linked to liver disease, while the other proposes to develop a lipid nanoparticle platform for hepatic stellate cell-specific drug delivery.

Mount Sinai New York

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October 02, 2025

Probing the Power of Hepatocyte Regeneration to Treat Chronic Liver Disease

While scientists have made significant strides in detailing the mechanisms of regeneration in healthy livers, less understood is what happens in an ailing liver. In chronic diseases such as MASH, hepatocytes are less able to regenerate as the illness progresses. One question is whether they lose the ability entirely or whether some process—such as fibrosis—is blocking their regenerative capacity. A Mount Sinai researcher is using mouse models of MASH to try to learn more.

Mount Sinai New York

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September 15, 2025

FDA Approves First Intranasal Loop Diuretic

The FDA has approved Enbumyst offering a self-administered outpatient option for managing edema in patients with heart failure, liver disease, and kidney disease.

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