1. The systematic review in Frontiers of Dental Medicine identified high levels of heavy metals, including arsenic, cadmium, and lead in over-the-counter toothpastes.
2. The study included a comprehensive literature search across six databases and synthesized findings from 11 studies.
3. Heavy metal contamination in toothpaste samples raised concerns for human and environmental health.
4. Various detection methods were used, including atomic absorption spectrophotometry and inductively coupled plasma–mass spectrometry.
5. Regulatory oversight of heavy metal content in personal care products is crucial to mitigate potential risks.

Source: Frontiers in Dental Medicine