A 7-day cold water acclimation protocol was found to significantly improve cellular cold tolerance in young males through enhanced autophagic responses and reduced apoptotic signaling. Researchers observed that daily exposure to cold water for 60 minutes over a week-long period transitioned cellular response from autophagic dysfunction to improved cytoprotective mechanisms. The study's findings indicate that cold exposure may be a viable approach to enhance autophagic function and potentially contribute to improvements in human health.

Source: Advanced Biology