June 18, 2026

Cell Aging May Predict Future Disease

Plasma proteomic models of more than 40 cell types were associated with incident Alzheimer's disease, amyotrophic lateral sclerosis, cancer,  and mortality across three large cohorts.

Conexiant

June 17, 2026

Side Effects: The Hidden Variable

The partner in the next room, the hormone in the blister pack, the cat on the couch, the minute-long chair stand. Several new studies suggest the factor shaping outcomes may be the one clinicians aren’t routinely measuring.

Conexiant

June 17, 2026

Pregnancy Risks With First Trimester GLP-1 Continuation

Claims-based target trial emulation found no clear association between continued GLP-1 receptor agonist use in early pregnancy and nonlive birth, fetal growth abnormalities, or major congenital malformations.

Conexiant

June 16, 2026

ACP Suggests First-Line Obesity Drugs

Semaglutide and tirzepatide had the greatest net benefit among evaluated treatments, the committee concluded.

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June 15, 2026

Does Weight Loss Intervention Improve Persistent AF?

Randomized trial found significant weight loss did not improve atrial fibrillation severity or burden in older patients with persistent disease.

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June 12, 2026

Combo Therapy May Improve HbA1c in Type 2 Diabetes

Oral orforglipron could be more effective in reducing hemoglobin A1c and body weight, with no increased risk of hypoglycemia in patients with inadequately controlled type 2 diabetes.

Conexiant

June 11, 2026

When Bad Data Enters the Drug Pipeline

Federal prosecutors allege that a Florida physician and research staff fabricated clinical trial records that were submitted into database systems used to evaluate investigational drugs.

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June 11, 2026

Medical Oddities: The Economics of Shut-Eye

Sleep became a commodity, tea became a therapy, and cats got a reprieve this week.

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June 11, 2026

Iron Deficiency Guidance Varies in Premenopausal Women

A Beyond the Guidelines discussion highlighted uncertainty around gastrointestinal evaluation and intravenous iron use in premenopausal women with iron deficiency.

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June 11, 2026

Higher-Dose Prenatal Vitamin D Linked to Memory Scores

Children exposed to higher-dose prenatal vitamin D scored modestly higher on verbal and visual memory tests at age 10 years, although overall intelligence and most cognitive measures did not differ significantly.

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