February 06, 2025

Meds that May Increase Dementia Risk

Antimicrobials, anti-inflammatories, and vaccines were associated with reduced dementia risk, while antipsychotics, antidepressants, and diabetes medications were frequently associated with increased dementia risk.

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February 05, 2025

Factors Influencing Denosumab Efficacy in SLE Osteoporosis Identified

Denosumab efficacy in treating osteoporosis in SLE patients can be predicted by baseline BMD, SLEDAI-2K scores, and hydroxychloroquine use.

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January 16, 2025

New XLH Guidelines Shift Primary Therapy to Burosumab

"Burosumab treatment normalized ALP serum levels in about 80% of both pediatric and adolescent cohorts, suggesting a substantial improvement of rickets in these patients," report authors of comprehensive new evidence-based recommendations for X-linked hypophosphatemia management.

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January 16, 2025

Bone Density Risks in Cancer Survivors

Discover how cancer treatments, lifestyle factors, and comorbidities contribute to long-term bone mineral density deficits in childhood cancer survivors.

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January 15, 2025

Bertagnolli to Exit NIH Director Role

NIH director, Dr. Monica M. Bertagnolli, is stepping down after launching major initiatives in women's health and long COVID research, indicating optimism for their continuation under new leadership.

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July 10, 2024

OA Linked to Higher Multimorbidity Risk, Study

A 20-year study reveals that patients with osteoarthritis have a higher risk of severe multimorbidity, emphasizing the need for comprehensive health care strategies beyond joint health.

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July 26, 2024

Peak Age for Best Olympic Performance

Why 27 may be the magic number for peak athletic performance.

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October 22, 2024

Notch Signaling: New Target in Early RA

A study reveals that while Notch signaling drives early RA pathology through neovascularization, anti-TNF therapy specifically reduced JAG1/2 and DLL1/4 transcription in synovial tissue myeloid cells, but only in good responders (ΔDAS28 >1.2 with DAS28 ≤3.2 at 12 weeks).

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November 18, 2024

Leptin's Role in Energy Deficiency Syndromes

Researchers present new insights into Relative Energy Deficiency in Sport, emphasizing its impact on athletes and military personnel, and discussing potential prevention and treatment strategies.

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