New guidance positions GLP-1 and GLP-1/GIP therapies as frontline options for long-term weight management—with profound implications for cardiovascular outcomes, access equity, and chronic disease care.
A new review outlines updated strategies for diagnosing and managing type 2 diabetes, recommending earlier use of SGLT2 inhibitors and GLP-1 receptor agonists in patients with cardiovascular or kidney conditions.
New research links a common metabolic liver condition in older adults to elevated risk of sudden hearing loss, highlighting potential implications for screening and prevention.
A new systematic review and meta-analysis found that cannabis use is associated with an increased risk of major adverse cardiovascular events—including acute coronary syndrome, stroke, and cardiovascular death—based on data from more than 432 million individuals in 24 observational studies.
A human fasting study found that prolonged water-only fasting raised inflammatory and platelet activation markers, reduced amyloid beta proteins, and altered lipid and glucose metabolism, with most changes reversing after refeeding.
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A large national study of U.S. women ages 12 to 49 found that higher levels of testosterone and sex hormone–binding globulin were linked to lower odds of metabolic syndrome, with differences observed across racial and ethnic groups.
New research finds that heavy alcohol consumption consistently raises cardiovascular risks, while evidence for protective effects of light drinking remains inconclusive.
A new cross-sectional study in healthy adults found that chronic marijuana smoking and edible THC use were linked to reduced endothelial function, an early marker of vascular disease risk.