Swedish cohort shows weight normalization before young adulthood is associated with coronary disease risk comparable to peers with lifelong normal weight.
The oral PCSK9 inhibitor enlicitide decanoate achieved 58% LDL-C reduction in patients with heterozygous familial hypercholesterolemia, offering a potential alternative to injectable therapies.
Researchers examine the strengths and shortcomings of the current European Alliance of Associations for Rheumatology definition for difficult-to-treat rheumatoid arthritis.
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Arrowhead’s small interfering RNA therapy reduced triglycerides and lowered pancreatitis risk in the phase 3 PALISADE trial, providing a quarterly self-administered option for patients with familial chylomicronemia syndrome.
Adverse childhood experiences drive elevated all-cause mortality across medical conditions, with emergency department patients also showing nearly double the death rates.