Adverse childhood experiences drive elevated all-cause mortality across medical conditions, with emergency department patients also showing nearly double the death rates.
Adding aspirin to long-term oral anticoagulation in patients with chronic coronary syndrome increased mortality and major bleeding without improving cardiovascular outcomes.
At the highest tested dose, a single IV CRISPR therapy reduced LDL cholesterol by ~49% and triglycerides by ~55% at 60 days in patients with treatment-resistant dyslipidemia.
Patients with type 2 diabetes who developed urinary tract infections while taking sodium-glucose cotransporter-2 inhibitors faced higher heart and kidney risks.
Accelerometer data from over 85,000 UK Biobank participants reveal significant sex differences in physical activity benefits for heart disease prevention and survival.