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From the Journals

Study Links Vitamin D Levels and Inflammation to Fall Risk

Inflammation might modify the vitamin D and fall risk relationship, according to recently published research.

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A recent genetic epidemiological study examined the association between 25-hydroxyvitamin D levels, inflammation, and fall risk using observational and Mendelian randomization analyses. The study found that both low and high 25-hydroxyvitamin D levels were associated with an increased risk of falls in individuals with elevated C-reactive protein levels. This relationship was modified by inflammation, suggesting a nonlinear effect of 25-hydroxyvitamin D on fall risk. The researchers emphasized the need for further research to explore the potential impact of high-dose vitamin D supplementation on fall risk, specifically in individuals with chronic inflammation.

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