- Adults conceived during colder months show higher brown adipose tissue (BAT) activity and energy expenditure.
- The study analyzed five independent cohorts of healthy Japanese adults.
- Cold-induced thermogenesis and total energy expenditure were significantly higher among participants conceived during colder months.
- Season of conception indirectly influenced adult BMI through BAT activation.
- Exposure to cold temperatures prior to fertilization could impact offspring BAT activity.
Source: Nature Metabolism
