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Conexiant chevron_right Endocrinology chevron_right DIM Supplement Alters Estradiol Patch Metabolism
From the Journals

DIM Supplement Alters Estradiol Patch Metabolism

A retrospective study found that DIM supplements significantly changed estrogen metabolism in postmenopausal women using estradiol patches, suggesting a potential drug-supplement interaction that may affect hormone therapy outcomes.

Conexiant
Full Article Summary Notecard
  1. DIM is derived from cruciferous vegetables.
  2. Study included 1,458 postmenopausal women.
  3. Significant estrogen profile differences were observed between DIM users and non-users.
  4. DIM may induce cytochrome P450 enzymes, affecting hormone metabolism.
  5. Importance of healthcare providers discussing supplement use with patients on MHT.
  6. Future research needed to assess effects on therapeutic outcomes.

Source: Menopause

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