Guidelines from the Department of Health and Human Services recommend statins as primary prevention for people with HIV aged 40 to 75 years who have a 10-year ASCVD risk of 5% or higher.
The FDA has approved Abbott’s Tendyne system, the first transcatheter mitral valve replacement for patients with severe mitral annular calcification who are ineligible for open-heart surgery.
Over one-third of psoriasis patients had elevated hs-CRP despite biologic treatment and skin clearance, with obesity, female sex, and fatty liver disease identified as key predictors of residual inflammation.
A large Canadian study of 3,357 patients found that taking blood pressure medication at bedtime did not reduce deaths or heart events compared to morning dosing.
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A 30-year cohort study found that life-course factors—including BMI, blood pressure, and glucose—significantly influence chronic disease accumulation, but much of the risk remains unexplained.
Maternal obesity, gestational diabetes, and hypertensive disorders in pregnancy were linked to higher blood pressure in children from age 2 to 18, a study of over 12,000 mother-child pairs found.
The new guidance is intended to “foster drug product development, ANDA submission and approval, and ultimately provide increased access to generic drugs."