Mineralys Therapeutics receives FDA clearance for a phase II clinical trial investigating lorundrostat, an aldosterone synthase inhibitor, in patients with moderate-to-severe obstructive sleep apnea and hypertension.
NIH director, Dr. Monica M. Bertagnolli, is stepping down after launching major initiatives in women's health and long COVID research, indicating optimism for their continuation under new leadership.
In HFrEF patients, cardiovascular magnetic resonance-estimated pulmonary capillary wedge pressure "correlates with clinical and ultrasound markers of congestion," demonstrates potential as a non-invasive alternative to traditional pressure measurements.
Researchers are conducting the Moore4Medical trial to evaluate whether an eHealth intervention, consisting of a wrist device and a mobile application, can effectively manage blood pressure, sleep quality, and physical activity levels in adult patients with moderate obstructive sleep apnea and hypertension.
‘An increase of one unit in RC was linked to a 135% rise in the likelihood of developing endometriosis,’ positioning remnant cholesterol as a promising marker for risk assessment.
Transcatheter tricuspid-valve replacement reduced tricuspid regurgitation to a level that is mild or less in 95% of patients, with associated improvements in quality of life, functional capacity, and survival compared to medical therapy.