The FDA approves vutrisiran (Amvuttra) as the first RNAi therapeutic to reduce cardiovascular events and mortality in adults with transthyretin-mediated (ATTR) amyloidosis with cardiomyopathy.
A randomized trial found that heating the lower limbs increased exercise endurance in heart failure patients, with blood flow rising significantly after treatment.
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In a new study on the long-term health risks post–COVID-19 hospitalization, researchers reported an "increased risk of death or hospitalization for various organ disorders up to 30 months after discharge."
Cholesterol levels in cystic fibrosis patients were found to increase within 3 months of starting ivacaftor therapy, then returned to baseline by 18 months.
Women with adverse pregnancy outcomes had higher BMI, BP, and glucose 10 years before pregnancy and persistently elevated risks up to 15 years postpartum, a new cohort study finds.
Findings indicate that while non-inferiority was not established, the reduced-dose regimen resulted in fewer bleeding complications without a marked increase in venous thromboembolism (VTE) recurrence.