"Use of GLP1-RAs and SGLT-2is was associated with reduced rates of 3P-MACE and HHF compared to DPP-4is, independent of age" - findings from a Danish nationwide study of 35,679 patients aged 70 and older with T2D.
"Readers should not have to infer what was probably done; they should be told explicitly." This principle drives the comprehensive CONSORT 2025 update, with its 7 new checklist items aimed at improving clinical trial transparency.
Mavacamten's phase III trial for nonobstructive hypertrophic cardiomyopathy does not show significant improvement in functional capacity or symptoms, reflecting challenges in less severe populations. Bristol Myers Squibb plans to present full data at a future scientific meeting.
Most relaxation interventions were associated with short-term reductions in blood pressure among adults with hypertension, according to a network meta-analysis of 182 randomized trials.
Bilateral ovary removal may increase heart failure risk 1.5-fold, with White women and younger patients facing double the risk, according to new research presented at ACC.25.
March’s FDA approvals feature new biosimilars, first-in-class therapies, expanded indications, and diagnostic innovations across allergy, cardiology, gastroenterology, infectious diseases, and more.