November 24, 2025

Oral PCSK9 Inhibitor Tied to LDL-C Drop

The oral PCSK9 inhibitor enlicitide decanoate achieved 58% LDL-C reduction in patients with heterozygous familial hypercholesterolemia, offering a potential alternative to injectable therapies.

Conexiant

November 21, 2025

EULAR: Issues With the RA Definition?

Researchers examine the strengths and shortcomings of the current European Alliance of Associations for Rheumatology definition for difficult-to-treat rheumatoid arthritis.

Conexiant

November 21, 2025

Which Antidepressants Shift Physiology?

Researchers found differences in how antidepressants affect weight, blood pressure, heart rate, and other physiological parameters.

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November 20, 2025

Root Canals: The Systemic Effect

Two-year study finds successful endodontic therapy associated with improved glucose and lipid metabolism in patients with apical periodontitis.

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November 18, 2025

Plozasiran Wins FDA Nod for FCS

Arrowhead’s small interfering RNA therapy reduced triglycerides and lowered pancreatitis risk in the phase 3 PALISADE trial, providing a quarterly self-administered option for patients with familial chylomicronemia syndrome.

Conexiant

November 14, 2025

The Risk Factor Going Unscreened

Adverse childhood experiences drive elevated all-cause mortality across medical conditions, with emergency department patients also showing nearly double the death rates.

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November 12, 2025

This Week’s Biopharma News: Clinical Hold for Heart Disease Gene Therapy

Our latest news roundup reports on Novartis’ new radioligand facility in California, new tech for boosting AAV yields, and MeiraGTx’s deal with Eli Lilly

The Medicine Maker

November 12, 2025

Dual Therapy for Coronary Disease: How Safe Is It? 

Adding aspirin to long-term oral anticoagulation in patients with chronic coronary syndrome increased mortality and major bleeding without improving cardiovascular outcomes.

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November 12, 2025

Adverse Pregnancy Outcomes Offer Early Clues to Future AF

Researchers found that adverse pregnancy outcomes increase women’s long-term risk of atrial fibrillation.

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