A UK trial-based economic evaluation found uncertain cost-effectiveness at 12 months, but a model extrapolating outcomes to 24 months estimated a lower cost per quality-adjusted life year for immediate surgery.
From breathier speech to breastfeeding history, metamaterial eye coils, and antifibrotic GLP-1 effects in mice, this week’s studies remind us that the most interesting signal is often hiding somewhere clinicians were not looking.
A four-factor staging system stratified response rates from 90.9% to 37.5% in a retrospective cohort study, although the model showed only moderate discrimination (C statistic, 0.68) and requires external validation