Researchers from South Korea investigated the long-term oncologic outcomes of breast-conserving treatment (BCT) compared with mastectomy in patients with breast cancer carrying BRCA1 or BRCA2 pathogenic variants. The study included 575 South Korean female patients with a median follow-up of 8.3 years. The results, published in JAMA Network Open, indicated that there were no significant differences in oncologic outcomes between the BCT and mastectomy groups, suggesting that BCT is a safe and effective surgical option for these patients, offering comparable long-term oncologic outcomes to mastectomy.

Source: JAMA Network Open