Researchers found that magnetic resonance neurography (MRN) more often provided perceived additional diagnostic value than high-resolution ultrasound (HRUS) in patients with suspected upper-extremity peripheral neuropathies involving proximal, extensive, or multi-nerve disease. In a retrospective subanalysis of 800 patients who underwent both imaging modalities, MRN accounted for 261 of 275 cases with added diagnostic value, while HRUS accounted for 14 cases, primarily when MRN was limited by metal artifacts. Proximal lesion location, multi-anatomical-region involvement, and multi-nerve disease independently favored MRN, supporting a more individualized imaging approach in complex neuropathy cases.