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Conexiant chevron_right Pediatrics chevron_right Neurological Soft Signs in PANS Linked to Disease Severity
From the Journals

Neurological Soft Signs in PANS Linked to Disease Severity

Neurological soft signs were present in 79.8% of patients with pediatric acute-onset neuropsychiatric syndrome, and severity increased alongside more NSSs.

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  1. High prevalence of neurological soft signs (NSS) in children with PANS
  2. Patients with four or more NSSs had higher Global Impairment Scores and more PANS symptoms
  3. NSS presence correlated with increased impairment and symptom count
  4. Targeted neurological examinations recommended to support PANS diagnosis
  5. Further research proposed into PANS pathophysiology
  6. Study limitations include variability in neurological exams and incomplete screenings

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