- Long-term study of pediatric patients treated with therapeutic hypothermia for neonatal encephalopathy.
- Neurodevelopmental issues emerged or worsened by age 8 to 10, despite normal early assessments.
- Motor performance declined nonlinearly over time; cognitive outcomes were stable in most children.
- Behavioral issues, internalizing symptoms, and additional late-onset conditions became more prominent with age.
- Early developmental testing did not reliably predict later difficulties.
- Importance of sustained follow-up and ongoing monitoring for timely intervention and support.
Source: The Journal of Pediatrics
