- Lithium adjunct therapy may benefit adolescents with severe emotional dysregulation.
- Significant symptom improvement noted at 6 months for lithium group.
- No statistically significant differences at 12 months.
- Adverse effects more common in lithium group, including weight gain and sedation.
- Adherence rates comparable between groups.
- Limitations include small sample size and lack of randomization.
Source: Journal of Clinical Medicine