- GLP-1 RAs lower A1C, fasting glucose, weight, and blood pressure in youth.
- 18 trials included 1,402 participants aged 6-17 years.
- Average weight loss: 3 kg, 5 kg in obesity-focused studies.
- GI adverse events like nausea and vomiting were common.
- Study duration was about 6 months with 2 months follow-up.
Source: JAMA Pediatrics
