A 69-year-old woman developed progressive gingival swelling, weight loss, and recurrent nasal bleeding. Imaging showed pulmonary nodules and biopsy confirmed necrotizing vasculitis with multinucleated giant cells. What’s your diagnosis?
The FDA has granted accelerated approval to Vanrafia (atrasentan) for reducing proteinuria in adults with primary immunoglobulin A nephropathy who are at risk of rapid disease progression.