- Phase 3 trial of toripalimab in nasopharyngeal carcinoma.
- Median follow-up: 37 months.
- 3-year FFS: 88.3% (cisplatin-sparing) vs 87.6% (standard).
- Fewer adverse events in cisplatin-sparing group.
- 532 patients enrolled across 13 hospitals in China.
- Limitations: patient demographics and lack of long-term toxicity data.
- Future trials assess PD-1 blockade combinations.
Source: JAMA