Clinical Report: SEE Program Strengthens Adherence

Overview

The Support, Educate, Empower (SEE) program significantly improved medication adherence and reduced glaucoma-related distress compared to standard education. A randomized clinical trial demonstrated that participants in the SEE program had a mean adherence of 78%, with over half achieving at least 80% adherence.

Background

Medication adherence is a critical factor in managing glaucoma, as poor adherence can lead to disease progression and increased healthcare costs. Traditional education methods often fail to engage patients effectively. The SEE program utilizes motivational interviewing and personalized coaching to enhance adherence and reduce distress associated with glaucoma management.

Data Highlights

Key Findings

• The SEE program improved electronically monitored adherence from 64% at baseline to 78% at 6 months.
• 55% of SEE participants achieved at least 80% adherence compared to 24% in the control group.
• The intervention led to a significant reduction in glaucoma-related distress, particularly in emotional burden and regimen-related distress.
• Improvements in adherence exceeded the prespecified minimally important clinical difference.
• The program's design allows for scalability and personalization, enhancing its effectiveness compared to traditional methods.

Clinical Implications

Healthcare providers should consider implementing structured, motivational interviewing-based programs like SEE to improve medication adherence in glaucoma patients. Such interventions can also alleviate distress, potentially leading to better overall patient outcomes.

Conclusion

The SEE program demonstrates that personalized coaching and education can significantly enhance medication adherence and reduce distress in glaucoma patients. Future studies should evaluate its long-term impact on clinical outcomes.

References

1. JAMA Ophthalmology, 2026 -- Effect of the Support, Educate, Empower Personalized Glaucoma Coaching Program on Medication Adherence
2. Optometric Management, 2025 -- Utilizing Staff for Patient Adherence
3. Ophthalmology Management, 2023 -- Medication Adherence Interventions That Work
4. The ASCO Post, 2014 -- UC Davis Comprehensive Cancer Center Tailors Pilot Program to Help Patients Adhere to Oral Chemotherapy
5. Drugs - Real World Outcomes — Pharmacist-Led Strategies to Enhance Adherence to Specialty Medications: Protocol for a Randomized Controlled Trial
6. Primary Open-Angle Glaucoma Preferred Practice Pattern
7. Cochrane Review on Behavioral Components in Glaucoma
8. Effect of the Support, Educate, Empower Personalized Glaucoma Coaching Program on Medication Adherence: The SEE Program Randomized Clinical Trial - PMC
9. Randomized controlled trial of an education-based intervention to improve medication adherence: Design considerations in the medication adherence in glaucoma to improve care study - PMC