July 10, 2025

A Powerful Team Researches Re-irradiation Options for Breast Cancer Recurrence

When breast cancer returns in a previously treated breast, the standard approach has been salvage mastectomy. The recently launched BRASIL trial (NCT06867484) aims to challenge this paradigm by investigating whether carefully selected patients can safely undergo repeat breast conservation with partial re-irradiation.

Baptist Health South Florida

July 09, 2025

PP-007: A First-in-Class Neuroprotective Agent Moves into Phase 3 Stroke Trial

A novel investigational compound, PP-007 (PEGylated carboxyhemoglobin), is advancing to a global Phase 3 clinical trial as a potential breakthrough in the treatment of acute ischemic stroke

Baptist Health South Florida

July 08, 2025

FIU Health Physicians to Practice Under Baptist Health as Part of FIU Clinical and Academic Alliance

Baptist Health and Florida International University (FIU) Herbert Wertheim College of Medicine have formed a strategic alliance that aims to enhance patient care, physician training and clinical research in South Florida.

Baptist Health South Florida

July 02, 2025

Lean Body Mass–Based Oxaliplatin Dosing and Risk of Neurotoxicity in Adjuvant Treatment of Stage III Colon Cancer

In a French phase II trial (LEANOX) reported in the Journal of Clinical Oncology, Assenat et al examined survival outcomes and oxaliplatin-induced peripheral neurotoxicity risk associated with lean bo...

The ASCO Post

July 02, 2025

Can Genetic Testing Identify the Best Treatment for Metastatic, Castration-Resistant Prostate Cancer?

Patients with metastatic, castration-resistant prostate cancer (mCRPC) have a median overall survival of only about two to three years, but genomic sequencing is making inroads against that grim prognosis.

Roswell Park Comprehensive Cancer Center

July 01, 2025

Survey Shows Inaccuracies in U.S. Perceptions of Testicular Cancer

Only about 13% of U.S. adults correctly reported that testicular cancer is most common among men younger than 40.

The ASCO Post

July 01, 2025

Metastatic Castration-Resistant Prostate Cancer: Comparison of Second-Line Regimens

As reported in The Lancet Oncology by Agarwal et al, the phase III CONTACT-02 trial examined the survival benefit of cabozantinib plus atezolizumab vs switch of androgen receptor pathway inhibitor (AR...

The ASCO Post

July 01, 2025

AI-Enhanced PACT as a Noninvasive Breast Imaging Alternative

Panoramic photoacoustic computed tomography (PACT) with machine learning assistance could be a safe, noninvasive, and sensitive alternative to mammography, ultrasound, and MRI for breast cancer screen...

The ASCO Post

July 01, 2025

HER3-DXd in NSCLC Without EGFR-Activating Mutations

As reported in the Journal of Clinical Oncology by Steuer et al, findings in a cohort of a phase I trial indicated activity of the HER3-directed antibody-drug conjugate patritumab deruxtecan (HER3-DXd...

The ASCO Post