A registry-based analysis of 4,636 cervical cancer cases in Puerto Rico found declining hysterectomy-corrected incidence among women younger than 35 years from 2019 to 2023, while women aged 35 to 49 years experienced the only statistically significant long-term increase across the 2001 to 2023 study period. Overall corrected incidence increased through 2014 before declining through 2023, although rates remained above 11.5 cases per 100,000 women and above the World Health Organization elimination target. Researchers noted that recent declines among younger women were temporally consistent with human papillomavirus vaccination uptake but cautioned that the study lacked patient-level vaccination and screening data.