Remote assessments detected memory changes over 30 weeks in patients with mild cognitive impairment, whereas conventional neuropsychological testing did not detect differences in short-term decline.
When fiber metabolism falters in lupus, the microbiome may start dining on the host instead. This week: mucin-munching bugs, brain-delivered DHA with no cognitive payoff, and lipid-loaded MS lesions that may not be innocent bystanders.
In two population-based cohorts, metabolically unhealthy status generally showed higher dementia risk estimates, while metabolically healthy obesity was not associated with increased risk in primary analyses.
Acidic gum beat sugar-free at cranking out nitric oxide from beetroot juice — exactly backward from what test-tube studies predicted. Also this week: a sleep gene that ignores amyloid, and jackfruit sap moonlighting as a bone-building drug delivery system.
Machine-learning models trained on routine patient-physician conversations achieved similar performance in development and external validation cohorts in predicting cognitive impairment.