- Comparative study of tenecteplase and alteplase in acute ischemic stroke patients, finding similar short-term efficacy and safety profiles.
- Tenecteplase emerged as a reasonable alternative, particularly in patients with large vessel occlusion not eligible for endovascular thrombectomy.
- Study suggests potential workflow efficiency improvements with tenecteplase due to its simpler administration protocol.
- Safety profiles were reassuringly similar for both agents, with comparable rates of symptomatic intracranial hemorrhage and mortality.
Source: JAMA Network Open
